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Best biotech stocks
Biotech is binary at the clinical stage and boring at the commercial stage; the two should never be held with the same position sizing.
The screen: 5 US exchange-listed companies in Health Care, 2 of which pay a dividend. Size mix: 4 large-cap, 1 mid-cap.
What separates the winners from the losers here
- Cash runway measured in quarters
- Whether the lead asset is de-risked past Phase II
- Partnership and royalty structure
The full list
| Ticker | Company | What it is |
|---|---|---|
| AMGN | Amgen | Biologics portfolio with an obesity pipeline option. |
| GILD | Gilead Sciences | HIV franchise funding oncology expansion. |
| VRTX | Vertex Pharmaceuticals | Cystic fibrosis monopoly extending into pain and kidney disease. |
| REGN | Regeneron | Antibody science with meaningful royalty economics. |
| MRNA | Moderna | mRNA platform seeking a second commercial franchise. |
Where to buy them
To hold these as real shares you need a stockbroker rather than a CFD provider. If you only want exposure to the price movement, a share CFD does that with leverage — and without ownership.
Compare every broker for US stocks →
Frequently asked questions
How many biotech stocks are in this list?
5, drawn from our US exchange-listed universe and spread across 1 sector. 2 of them pay a dividend.
Is this a list of biotech stocks to buy?
No. It is a screen — a defined, reproducible filter over a stated universe. A screen tells you which companies share a characteristic; it says nothing about whether the price you would pay today is a sensible one. Nothing here is investment advice.
What is the main risk with biotech stocks?
Clinical-stage names routinely fall 60–80% in a single session on trial data. Size accordingly or do not hold them.
How do I actually buy these from outside the US?
You need a broker that accepts your country of residence and gives you access to US exchanges. To own the shares outright, that usually means an international stockbroker plus a W-8BEN form to claim your treaty rate on dividend withholding.
Screen definition reviewed August 2026. Universe: US exchange-listed securities tracked by InvestingTrading. This page is information, not investment advice.